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A malignant hyperthermia–inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels

Bidirectional communication between the 1,4-dihydropyridine receptor (DHPR) in the plasma membrane and the type 1 ryanodine receptor (RYR1) in the sarcoplasmic reticulum (SR) is responsible for both skeletal-type excitation–contraction coupling (voltage-gated Ca(2+) release from the SR) and increase...

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Detalles Bibliográficos
Autores principales:	Bannister, Roger A., Estève, Eric, Eltit, José M., Pessah, Isaac N., Allen, Paul D., López, José R., Beam, Kurt G.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888063/ https://www.ncbi.nlm.nih.gov/pubmed/20479108 http://dx.doi.org/10.1085/jgp.200910329

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