Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints

INTRODUCTION: Inflammatory joint destruction in rheumatoid arthritis (RA) may be triggered by autoantibodies, the production of which is supported by autoreactive T cells. Studies on RA and animal models of the disease suggest that T cells recruited in the joints can locally initiate or propagate ar...

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Detalles Bibliográficos
Autores principales: Angyal, Adrienn, Egelston, Colt, Kobezda, Tamás, Olasz, Katalin, László, Anna, Glant, Tibor T, Mikecz, Katalin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888192/
https://www.ncbi.nlm.nih.gov/pubmed/20298547
http://dx.doi.org/10.1186/ar2954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888192/
https://www.ncbi.nlm.nih.gov/pubmed/20298547
http://dx.doi.org/10.1186/ar2954

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