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Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints
INTRODUCTION: Inflammatory joint destruction in rheumatoid arthritis (RA) may be triggered by autoantibodies, the production of which is supported by autoreactive T cells. Studies on RA and animal models of the disease suggest that T cells recruited in the joints can locally initiate or propagate ar...
Autores principales: | Angyal, Adrienn, Egelston, Colt, Kobezda, Tamás, Olasz, Katalin, László, Anna, Glant, Tibor T, Mikecz, Katalin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888192/ https://www.ncbi.nlm.nih.gov/pubmed/20298547 http://dx.doi.org/10.1186/ar2954 |
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