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Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation

INTRODUCTION: The endoplasmic reticulum (ER) stress-response, evoked in mice by the overexpression of class I major histocompatibility complex antigen (MHC-I), was proposed as a major mechanism responsible for skeletal muscle damage and dysfunction in autoimmune myositis. The present study was under...

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Detalles Bibliográficos
Autores principales: Vitadello, Maurizio, Doria, Andrea, Tarricone, Elena, Ghirardello, Anna, Gorza, Luisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888201/
https://www.ncbi.nlm.nih.gov/pubmed/20334640
http://dx.doi.org/10.1186/ar2963

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