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Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

INTRODUCTION: Interleukin (IL)-17 is a proinflammatory cytokine that is produced largely by a unique CD4(+ )T-helper (Th) subset called Th17 cells. The development of Th17 cells is suppressed by interferon (IFN)-γ produced by Th1 cells, suggesting cross-regulation between Th17 and Th1 cells. Thus, t...

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Detalles Bibliográficos
Autores principales: Shah, Kamini, Lee, Won-Woo, Lee, Seung-Hyun, Kim, Sang Hyun, Kang, Seong Wook, Craft, Joe, Kang, Insoo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888202/
https://www.ncbi.nlm.nih.gov/pubmed/20334681
http://dx.doi.org/10.1186/ar2964