Cargando…

B cell depletion in diffuse progressive systemic sclerosis: safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial

INTRODUCTION: An over-expression of CD19 has been shown in B cells of systemic sclerosis (SSc) and B cells are thought to contribute to the induction of skin fibrosis in the tight skin mouse model. The aim was to define the outcome on safety and the change in skin score after rituximab therapy in SS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bosello, Silvia, De Santis, Maria, Lama, Gina, Spanò, Cristina, Angelucci, Cristiana, Tolusso, Barbara, Sica, Gigliola, Ferraccioli, Gianfranco
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888203/ https://www.ncbi.nlm.nih.gov/pubmed/20338043 http://dx.doi.org/10.1186/ar2965

Ejemplares similares

Characterization of inflammatory cell infiltrate of scleroderma skin: B cells and skin score progression
por: Bosello, Silvia, et al.
Publicado: (2018)

Multifaceted Functional Role of Semaphorins in Glioblastoma
por: Angelucci, Cristiana, et al.
Publicado: (2019)

Leuprorelin Acetate Long-Lasting Effects on GnRH Receptors of Prostate Cancer Cells: An Atomic Force Microscopy Study of Agonist/Receptor Interaction
por: Lama, Gina, et al.
Publicado: (2013)

Very early rheumatoid arthritis is the major predictor of major outcomes: clinical ACR remission and radiographic non-progression
por: Bosello, Silvia, et al.
Publicado: (2011)

Systemic Bone Density at Disease Onset Is Associated With Joint Erosion Progression in Early Naive to Treatment Rheumatoid Arthritis: A Prospective 12-Month Follow-Up Open-Label Study
por: Bruno, Dario, et al.
Publicado: (2021)

Memory B cell subsets and plasmablasts are lower in early than in long-standing Rheumatoid Arthritis
por: Fedele, Anna Laura, et al.
Publicado: (2014)

Thymosin β(4) and β(10) in Sjögren’s syndrome: saliva proteomics and minor salivary glands expression
por: Bosello, Silvia, et al.
Publicado: (2016)

Functional, radiological and biological markers of alveolitis and infections of the lower respiratory tract in patients with systemic sclerosis
por: De Santis, Maria, et al.
Publicado: (2005)

Analysis of angiogenesis related factors in glioblastoma, peritumoral tissue and their derived cancer stem cells
por: D'Alessio, Alessio, et al.
Publicado: (2016)

Could we use a lower dose of rituximab to treat rheumatoid arthritis in clinical practice: pros and cons?
por: Ferraccioli, Gianfranco, et al.
Publicado: (2016)

β-thymosins and interstitial lung disease: study of a scleroderma cohort with a one-year follow-up
por: De Santis, Maria, et al.
Publicado: (2011)

PTPN22 1858C>T Polymorphism Distribution in Europe and Association with Rheumatoid Arthritis: Case-Control Study and Meta-Analysis
por: Totaro, Michele Ciro, et al.
Publicado: (2011)

Cancer stem cells from peritumoral tissue of glioblastoma multiforme: the possible missing link between tumor development and progression
por: Angelucci, Cristiana, et al.
Publicado: (2018)

Do we need to apply a T2T strategy even in ACPA-negative early rheumatoid arthritis? YES
por: Ferraccioli, Gianfranco, et al.
Publicado: (2016)

Obesity as a Risk and Severity Factor in Rheumatic Diseases (Autoimmune Chronic Inflammatory Diseases)
por: Gremese, Elisa, et al.
Publicado: (2014)

Epithelial-Stromal Interactions in Human Breast Cancer: Effects on Adhesion, Plasma Membrane Fluidity and Migration Speed and Directness
por: Angelucci, Cristiana, et al.
Publicado: (2012)

Thirty-six studies or caprices for the violin
por: Fiorillo, Federigo, 1755-ca. 1823
Publicado: (1895)

Isolation of Cancer Stem Cells from Three Human Glioblastoma Cell Lines: Characterization of Two Selected Clones
por: Iacopino, Fortunata, et al.
Publicado: (2014)

Pivotal role of human stearoyl-CoA desaturases (SCD1 and 5) in breast cancer progression: oleic acid-based effect of SCD1 on cell migration and a novel pro-cell survival role for SCD5
por: Angelucci, Cristiana, et al.
Publicado: (2018)

Allele *2 of the HS1,2A enhancer of the Ig regulatory region associates with rheumatoid arthritis
por: Tolusso, B, et al.
Publicado: (2008)

Progress of Epidemics in Thirty-Six Towns and Districts
Publicado: (1856)

JAK inhibition by methotrexate (and csDMARDs) may explain clinical efficacy as monotherapy and combination therapy
por: Gremese, Elisa, et al.
Publicado: (2019)

Immunohistochemical Analysis of DNA Repair- and Drug-Efflux-Associated Molecules in Tumor and Peritumor Areas of Glioblastoma
por: Angelucci, Cristiana, et al.
Publicado: (2021)

The Role of High-Mobility Group Box-1 and Its Crosstalk with Microbiome in Rheumatoid Arthritis
por: Biscetti, Federico, et al.
Publicado: (2017)

The forgotten key players in rheumatoid arthritis: IL-8 and IL-17 – Unmet needs and therapeutic perspectives
por: Gremese, Elisa, et al.
Publicado: (2023)

Biomarkers of Good EULAR Response to the B Cell Depletion Therapy in All Seropositive Rheumatoid Arthritis Patients: Clues for the Pathogenesis
por: Ferraccioli, Gianfranco, et al.
Publicado: (2012)

The complete double bass parts of thirty-six overtures /

Six month-follow up of laparoscopic sleeve gastrectomy
por: Keleidari, Behrouz, et al.
Publicado: (2016)

Tapering and discontinuation of TNF-α blockers without disease relapse using ultrasonography as a tool to identify patients with rheumatoid arthritis in clinical and histological remission
por: Alivernini, Stefano, et al.
Publicado: (2016)

Age-Related Alterations at Neuromuscular Junction: Role of Oxidative Stress and Epigenetic Modifications
por: Dobrowolny, Gabriella, et al.
Publicado: (2021)

Thirty-Six-Month Follow-up of Diaphragm Pacing with Phrenic Nerve Stimulation for Ventilator Dependence in Traumatic Tetraplegia: The Way Forward for Spinal Cord Injury Rehabilitation in a Developing Country
por: Sharma, Vyom, et al.
Publicado: (2021)

Anemia status of infants and young children aged six to thirty-six months in Ma'anshan City: A retrospective study
por: Wang, Xue-Mei, et al.
Publicado: (2023)

Thirty-six elementary and progressive studies for the violin, op. 20 /
por: Kayser, H. E. [Heinrich Ernst], 1815-1888
Publicado: (1915)

Tumour of Breast Recurrent Six Times during Thirty Years
por: Greig, David M.
Publicado: (1913)

Very early rheumatoid arthritis as a predictor of remission: a multicentre real life prospective study
por: Gremese, Elisa, et al.
Publicado: (2013)

Computer-Aided Quantification of Interstitial Lung Disease from High Resolution Computed Tomography Images in Systemic Sclerosis: Correlation with Visual Reader-Based Score and Physiologic Tests
por: Salaffi, Fausto, et al.
Publicado: (2015)

Six-Month Follow-Up Study of Ultrarapid Opiate Detoxification With Naltrexone
por: Forozeshfard, Mohammad, et al.
Publicado: (2014)

Peripheral blood CD4(pos)CD25(pos)FoxP3(pos) cells and inflammatory cytokines as biomarkers of response in rheumatoid arthritis patients treated with CTLA4-Ig
por: Elisa, Gremese, et al.
Publicado: (2022)

Correction: Peripheral blood CD4(pos)CD25(pos)FoxP3(pos) cells and inflammatory cytokines as biomarkers of response in rheumatoid arthritis patients treated with CTLA4-Ig
por: Gremese, Elisa, et al.
Publicado: (2022)

Six-month multidisciplinary follow-up in multisystem inflammatory syndrome in children: An Italian single-center experience
por: Zuccotti, Gianvincenzo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mgaac4bb531gj9pukhutgtr8md