Cargando…
A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis
INTRODUCTION: Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that mainly affects synovial joints. Biologics directed against tumor-necrosis-factor (TNF)-α are efficacious in the treatment of RA. However, the role of TNF receptor-1 (TNFR1) in mediating the TNFα effects in RA has not...
Autores principales: | Arntz, Onno J, Geurts, Jeroen, Veenbergen, Sharon, Bennink, Miranda B, van den Brand, Ben T, Abdollahi-Roodsaz, Shahla, van den Berg, Wim B, van de Loo, Fons A |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888212/ https://www.ncbi.nlm.nih.gov/pubmed/20370892 http://dx.doi.org/10.1186/ar2974 |
Ejemplares similares
-
Trapped in a vicious loop: Toll-like receptors sustain the spontaneous cytokine production by rheumatoid synovium
por: Abdollahi-Roodsaz, Shahla, et al.
Publicado: (2011) -
Intravenous Delivery of HIV-Based Lentiviral Vectors Preferentially Transduces F4/80+ and Ly-6C+ Cells in Spleen, Important Target Cells in Autoimmune Arthritis
por: van den Brand, Ben T., et al.
Publicado: (2013) -
Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane
por: Broeren, Mathijs G. A., et al.
Publicado: (2016) -
Identification of a natural soluble form of the IL-18 receptor accessory protein as an immunomodulator in experimental arthritis
por: Smeets, RL, et al.
Publicado: (2005) -
Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis?
por: van de Loo, Fons A, et al.
Publicado: (2009)