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A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis

INTRODUCTION: Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that mainly affects synovial joints. Biologics directed against tumor-necrosis-factor (TNF)-α are efficacious in the treatment of RA. However, the role of TNF receptor-1 (TNFR1) in mediating the TNFα effects in RA has not...

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Detalles Bibliográficos
Autores principales: Arntz, Onno J, Geurts, Jeroen, Veenbergen, Sharon, Bennink, Miranda B, van den Brand, Ben T, Abdollahi-Roodsaz, Shahla, van den Berg, Wim B, van de Loo, Fons A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888212/
https://www.ncbi.nlm.nih.gov/pubmed/20370892
http://dx.doi.org/10.1186/ar2974

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