FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development

INTRODUCTION: Forkhead box p3 (FoxP3)-expressing regulatory T cells (Tregs) have been clearly implicated in the control of autoimmune disease in murine models. In addition, ectopic expression of FoxP3 conveys a Treg phenotype to CD4(+ )T cells, lending itself to therapeutic use in the prevention of...

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Detalles Bibliográficos
Autores principales: Haque, Rizwanul, Lei, Fengyang, Xiong, Xiaofang, Wu, Yuzhang, Song, Jianxun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888221/
https://www.ncbi.nlm.nih.gov/pubmed/20384988
http://dx.doi.org/10.1186/ar2983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888221/
https://www.ncbi.nlm.nih.gov/pubmed/20384988
http://dx.doi.org/10.1186/ar2983

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