B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy

INTRODUCTION: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory receptor for IgG immune complexes FcγRIIb (CD32b), on B cells from rheumatoid arthr...

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Detalles Bibliográficos
Autores principales: Catalán, Diego, Aravena, Octavio, Sabugo, Francisca, Wurmann, Pamela, Soto, Lilian, Kalergis, Alexis M, Cuchacovich, Miguel, Aguillón, Juan C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888223/
https://www.ncbi.nlm.nih.gov/pubmed/20398308
http://dx.doi.org/10.1186/ar2985

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