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Choline Promotes Nicotinic Receptor α4 + β2 Up-regulation

Neuronal nicotinic acetylcholine receptors (nAChR) composed of α4 + β2 subunits, the high affinity nicotine-binding site in the mammalian brain, up-regulate in response to chronic nicotine exposure. The identities of endogenous mediators of this process are unknown. We find that choline also up-regu...

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Detalles Bibliográficos
Autores principales:	Gahring, Lorise C., Vasquez-Opazo, Gustavo A., Rogers, Scott W.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888390/ https://www.ncbi.nlm.nih.gov/pubmed/20392695 http://dx.doi.org/10.1074/jbc.M110.108803

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