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Systematic Analysis of Cis-Elements in Unstable mRNAs Demonstrates that CUGBP1 Is a Key Regulator of mRNA Decay in Muscle Cells
BACKGROUND: Dramatic changes in gene expression occur in response to extracellular stimuli and during differentiation. Although transcriptional effects are important, alterations in mRNA decay also play a major role in achieving rapid and massive changes in mRNA abundance. Moreover, just as transcri...
Autores principales: | Lee, Jerome E., Lee, Ju Youn, Wilusz, Jeffrey, Tian, Bin, Wilusz, Carol J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888570/ https://www.ncbi.nlm.nih.gov/pubmed/20574513 http://dx.doi.org/10.1371/journal.pone.0011201 |
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