Increased Hepatic Insulin Action in Diet-Induced Obese Mice Following Inhibition of Glucosylceramide Synthase

BACKGROUND: Obesity is characterized by the accumulation of fat in the liver and other tissues, leading to insulin resistance. We have previously shown that a specific inhibitor of glucosylceramide synthase, which inhibits the initial step in the synthesis of glycosphingolipids (GSLs), improved gluc...

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Detalles Bibliográficos
Autores principales: Yew, Nelson S., Zhao, Hongmei, Hong, Eun-Gyoung, Wu, I-Huan, Przybylska, Malgorzata, Siegel, Craig, Shayman, James A., Arbeeny, Cynthia M., Kim, Jason K., Jiang, Canwen, Cheng, Seng H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888613/
https://www.ncbi.nlm.nih.gov/pubmed/20574539
http://dx.doi.org/10.1371/journal.pone.0011239

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