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Nanog Variability and Pluripotency Regulation of Embryonic Stem Cells - Insights from a Mathematical Model Analysis

The expression of the transcription factors Oct4, Sox2, and Nanog is commonly associated with pluripotency of mouse embryonic stem (ES) cells. However, recent observations suggest that ES cell populations are heterogeneous with respect to the expression of Nanog and that individual ES cells reversib...

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Detalles Bibliográficos
Autores principales:	Glauche, Ingmar, Herberg, Maria, Roeder, Ingo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888652/ https://www.ncbi.nlm.nih.gov/pubmed/20574542 http://dx.doi.org/10.1371/journal.pone.0011238

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