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Branched Intermediate Formation Stimulates Peptide Bond Cleavage in Protein Splicing
Protein splicing is a posttranslational modification in which an intein domain excises itself out of a host protein. Here, we investigate how the steps in the splicing process are coordinated so as to maximize the production of the final splice products and minimize the generation of undesired cleav...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889191/ https://www.ncbi.nlm.nih.gov/pubmed/20495572 http://dx.doi.org/10.1038/nchembio.371 |