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Albumin Uptake in OK Cells Exposed to Rotenone: A Model for Studying the Effects of Mitochondrial Dysfunction on Endocytosis in the Proximal Tubule?
BACKGROUND: The renal proximal tubule (PT) is clinically vulnerable to mitochondrial dysfunction; sub-lethal injury can lead to the Fanconi syndrome, with elevated urinary excretion of low-molecular-weight proteins. As the mechanism that couples mitochondrial dysfunction to impaired PT low-molecular...
Autores principales: | Hall, A.M., Campanella, M., Loesch, A., Duchen, M.R., Unwin, R.J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889685/ https://www.ncbi.nlm.nih.gov/pubmed/20484937 http://dx.doi.org/10.1159/000314540 |
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