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The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis
Prior information biases the decision process: actions consistent with prior information are executed swiftly, whereas actions inconsistent with prior information are executed slowly. How is this bias implemented in the brain? To address this question we conducted an experiment in which people had t...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889713/ https://www.ncbi.nlm.nih.gov/pubmed/20577592 http://dx.doi.org/10.3389/fnhum.2010.00040 |
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author | Forstmann, Birte U. Brown, Scott Dutilh, Gilles Neumann, Jane Wagenmakers, Eric-Jan |
author_facet | Forstmann, Birte U. Brown, Scott Dutilh, Gilles Neumann, Jane Wagenmakers, Eric-Jan |
author_sort | Forstmann, Birte U. |
collection | PubMed |
description | Prior information biases the decision process: actions consistent with prior information are executed swiftly, whereas actions inconsistent with prior information are executed slowly. How is this bias implemented in the brain? To address this question we conducted an experiment in which people had to decide quickly whether a cloud of dots moved coherently to the left or to the right. Cues provided probabilistic information about the upcoming stimulus. Behavioral data were analyzed with the linear ballistic accumulator (LBA) model, confirming that people used the cue to bias their decisions. The functional magnetic resonance imaging (fMRI) data showed that presentation of the cue differentially activated orbitofrontal cortex, hippocampus, and the putamen. Directional cues selectively activated the contralateral putamen. The fMRI analysis yielded results only when the LBA bias parameter was included as a covariate, highlighting the practical benefits of formal modeling. Our results suggest that the human brain uses prior information by increasing cortico-striatal activation to selectively disinhibit preferred responses. |
format | Text |
id | pubmed-2889713 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Frontiers Research Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-28897132010-06-24 The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis Forstmann, Birte U. Brown, Scott Dutilh, Gilles Neumann, Jane Wagenmakers, Eric-Jan Front Hum Neurosci Neuroscience Prior information biases the decision process: actions consistent with prior information are executed swiftly, whereas actions inconsistent with prior information are executed slowly. How is this bias implemented in the brain? To address this question we conducted an experiment in which people had to decide quickly whether a cloud of dots moved coherently to the left or to the right. Cues provided probabilistic information about the upcoming stimulus. Behavioral data were analyzed with the linear ballistic accumulator (LBA) model, confirming that people used the cue to bias their decisions. The functional magnetic resonance imaging (fMRI) data showed that presentation of the cue differentially activated orbitofrontal cortex, hippocampus, and the putamen. Directional cues selectively activated the contralateral putamen. The fMRI analysis yielded results only when the LBA bias parameter was included as a covariate, highlighting the practical benefits of formal modeling. Our results suggest that the human brain uses prior information by increasing cortico-striatal activation to selectively disinhibit preferred responses. Frontiers Research Foundation 2010-05-21 /pmc/articles/PMC2889713/ /pubmed/20577592 http://dx.doi.org/10.3389/fnhum.2010.00040 Text en Copyright © 2010 Forstmann, Brown, Dutilh, Neumann and Wagenmakers. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited. |
spellingShingle | Neuroscience Forstmann, Birte U. Brown, Scott Dutilh, Gilles Neumann, Jane Wagenmakers, Eric-Jan The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis |
title | The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis |
title_full | The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis |
title_fullStr | The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis |
title_full_unstemmed | The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis |
title_short | The Neural Substrate of Prior Information in Perceptual Decision Making: A Model-Based Analysis |
title_sort | neural substrate of prior information in perceptual decision making: a model-based analysis |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889713/ https://www.ncbi.nlm.nih.gov/pubmed/20577592 http://dx.doi.org/10.3389/fnhum.2010.00040 |
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