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Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode
A brush of 64 microwires was chronically implanted in the ventral premotor cortex of a macaque monkey. Contrary to common approaches, the wires were inserted from the white matter side. This approach, by avoiding mechanical pressure on the dura and pia mater during penetration, disturbed only minima...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889715/ https://www.ncbi.nlm.nih.gov/pubmed/20577628 http://dx.doi.org/10.3389/fneng.2010.00006 |
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author | Krüger, Jürgen Caruana, Fausto Volta, Riccardo Dalla Rizzolatti, Giacomo |
author_facet | Krüger, Jürgen Caruana, Fausto Volta, Riccardo Dalla Rizzolatti, Giacomo |
author_sort | Krüger, Jürgen |
collection | PubMed |
description | A brush of 64 microwires was chronically implanted in the ventral premotor cortex of a macaque monkey. Contrary to common approaches, the wires were inserted from the white matter side. This approach, by avoiding mechanical pressure on the dura and pia mater during penetration, disturbed only minimally the cortical recording site. With this approach isolated potentials and multiunit activity were recorded for more than 7 years in about one-third of electrodes. The indirect insertion method also provided an excellent stability within each recording session, and in some cases even allowed recording from the same neurons for several years. Histological examination of the implanted brain region shows only a very marginal damage to the recording area. Advantages and problems related to long-term recording are discussed. |
format | Text |
id | pubmed-2889715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Frontiers Research Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-28897152010-06-24 Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode Krüger, Jürgen Caruana, Fausto Volta, Riccardo Dalla Rizzolatti, Giacomo Front Neuroengineering Neuroscience A brush of 64 microwires was chronically implanted in the ventral premotor cortex of a macaque monkey. Contrary to common approaches, the wires were inserted from the white matter side. This approach, by avoiding mechanical pressure on the dura and pia mater during penetration, disturbed only minimally the cortical recording site. With this approach isolated potentials and multiunit activity were recorded for more than 7 years in about one-third of electrodes. The indirect insertion method also provided an excellent stability within each recording session, and in some cases even allowed recording from the same neurons for several years. Histological examination of the implanted brain region shows only a very marginal damage to the recording area. Advantages and problems related to long-term recording are discussed. Frontiers Research Foundation 2010-05-28 /pmc/articles/PMC2889715/ /pubmed/20577628 http://dx.doi.org/10.3389/fneng.2010.00006 Text en Copyright © 2010 Krüger, Caruana, Dalla Volta and Rizzolatti. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited. |
spellingShingle | Neuroscience Krüger, Jürgen Caruana, Fausto Volta, Riccardo Dalla Rizzolatti, Giacomo Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode |
title | Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode |
title_full | Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode |
title_fullStr | Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode |
title_full_unstemmed | Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode |
title_short | Seven Years of Recording from Monkey Cortex with a Chronically Implanted Multiple Microelectrode |
title_sort | seven years of recording from monkey cortex with a chronically implanted multiple microelectrode |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889715/ https://www.ncbi.nlm.nih.gov/pubmed/20577628 http://dx.doi.org/10.3389/fneng.2010.00006 |
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