Cargando…

Taking Aim at Islet Hormones With GLP-1: Is Insulin or Glucagon the Better Target?

Detalles Bibliográficos
Autor principal:	D'Alessio, David A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Commentaries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889753/ https://www.ncbi.nlm.nih.gov/pubmed/20587800 http://dx.doi.org/10.2337/db10-0299

Ejemplares similares

Is GLP‐1 a hormone: Whether and When?
por: D'Alessio, David
Publicado: (2016)

An Innate Disposition for a Healthier Gut: GLP-1R Signaling in Intestinal Epithelial Lymphocytes
por: Rosario, Wilfredo, et al.
Publicado: (2015)

Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon
por: Cabrera, Over, et al.
Publicado: (2021)

Glucagon-like peptide 1 (GLP-1)
por: Müller, T.D., et al.
Publicado: (2019)

GLP-1 Effects on Islets: Hormonal, Neuronal, or Paracrine?
por: Donath, Marc Y., et al.
Publicado: (2013)

Cardioprotective effects of GLP‐1(28‐36a): A degraded metabolite or GLP‐1’s better half?
por: Liu, Yangyang, et al.
Publicado: (2020)

A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets
por: Hodson, David J., et al.
Publicado: (2020)

Effect of Endogenous GLP-1 on Insulin Secretion in Type 2 Diabetes
por: Salehi, Marzieh, et al.
Publicado: (2010)

Glucagon, GLP-1 and Thermogenesis
por: González-García, Ismael, et al.
Publicado: (2019)

DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets
por: Hall, Elin, et al.
Publicado: (2013)

Incretin concept revised: The origin of the insulinotropic function of glucagon‐like peptide‐1 – the gut, the islets or both?
por: Yabe, Daisuke, et al.
Publicado: (2017)

Puzzling About Partial Glucagon Responses to Hypoglycemia in Intrahepatic Islet Recipients: Missing Pieces
por: Robertson, R. Paul
Publicado: (2015)

Gastric Bypass Surgery Enhances Glucagon-Like Peptide 1–Stimulated Postprandial Insulin Secretion in Humans
por: Salehi, Marzieh, et al.
Publicado: (2011)

The Insulin:Glucagon Ratio and the Choice of Glucose-Lowering Drugs
por: Kalra, Sanjay, et al.
Publicado: (2016)

Melatonin and Pancreatic Islets: Interrelationships between Melatonin, Insulin and Glucagon
por: Peschke, Elmar, et al.
Publicado: (2013)

Islets Transplanted Into the Eye: Do They Improve Our Insight Into Islet Adaptation to Insulin Resistance?
por: Satin, Leslie S., et al.
Publicado: (2016)

The dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide: a novel cardiometabolic therapeutic prospect
por: Fisman, Enrique Z., et al.
Publicado: (2021)

Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion
por: Ahlkvist, L, et al.
Publicado: (2013)

Clinical relevance of dual agonist of glucagon and glucagon‐like peptide‐1 receptors to achieve functional restoration of first‐ and second‐phase insulin secretion
por: Kimura, Tomohiko, et al.
Publicado: (2022)

The Role of Glucagon-Like Peptide 1 (GLP1) in Type 3 Diabetes: GLP-1 Controls Insulin Resistance, Neuroinflammation and Neurogenesis in the Brain
por: Bae, Choon Sang, et al.
Publicado: (2017)

How does glucagon‐like peptide 1 stimulate human β‐cell proliferation? A lesson from islet graft experiments
por: Fujitani, Yoshio
Publicado: (2018)

The Antidiabetic Mechanisms of Polyphenols Related to Increased Glucagon-Like Peptide-1 (GLP1) and Insulin Signaling
por: Domínguez Avila, J. Abraham, et al.
Publicado: (2017)

GLP-1R–Targeting Magnetic Nanoparticles for Pancreatic Islet Imaging
por: Wang, Ping, et al.
Publicado: (2014)

Gastric bypass alters both glucose-dependent and glucose-independent regulation of islet hormone secretion
por: Salehi, Marzieh, et al.
Publicado: (2015)

Postprandial Insulin Secretion After Gastric Bypass Surgery: The Role of Glucagon-Like Peptide 1
por: Holst, Jens Juul
Publicado: (2011)

Is Endogenous GLP-1 the Only Important Enhancer of Glucose-Induced Insulin Secretion in Type 2 Diabetes?
por: Deacon, Carolyn F.
Publicado: (2012)

Degradation of the Incretin Hormone Glucagon-Like Peptide-1 (GLP-1) by Enterococcus faecalis Metalloprotease GelE
por: LeValley, Stephanie L., et al.
Publicado: (2020)

Serum levels of glucagon-like peptide (GLP)-1 and GLP-2 in patients with Hashimoto's thyroiditis
por: Jin, Yue, et al.
Publicado: (2015)

AIMing 2 promote lupus by targeting helpers
por: Leavenworth, Jianmei W.
Publicado: (2022)

Allosteric Modulation of the Activity of the Glucagon-like Peptide-1 (GLP-1) Metabolite GLP-1 9–36 Amide at the GLP-1 Receptor
por: Li, Naichang, et al.
Publicado: (2012)

GLP-1/glucagon receptor co-agonism for treatment of obesity
por: Sánchez-Garrido, Miguel A., et al.
Publicado: (2017)

Glucagon‐like peptide‐1 (GLP‐1) receptor agonists and their cardiovascular benefits—The role of the GLP‐1 receptor
por: Helmstädter, Johanna, et al.
Publicado: (2021)

Effects of glucagon like peptide-1 to mediate glycemic effects of weight loss surgery
por: Salehi, Marzieh, et al.
Publicado: (2014)

Targeting Purinergic Receptors in Islet Transplantation
por: Aikin, Reid A.
Publicado: (2013)

Chewing the fat for better insulin secretion
por: Andrikopoulos, Sofianos
Publicado: (2015)

SAT-167 Intra-Islet Ghrelin Signaling Does Not Regulate Insulin Secretion from Adult Mice
por: Gray, Sarah, et al.
Publicado: (2019)

Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD
por: Seghieri, Marta, et al.
Publicado: (2018)

SIRT1 Takes a Backseat to AMPK in the Regulation of Insulin Sensitivity by Resveratrol
por: Fullerton, Morgan D., et al.
Publicado: (2010)

The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice
por: Ørgaard, Anne, et al.
Publicado: (2017)

Plasma levels of glucagon but not GLP-1 are elevated in response to inflammation in humans
por: Modrzynska, Justyna, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3phk4rpbivsjo2hslh8f7n2dfk