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PYY(3–36) and Oxyntomodulin Can Be Additive in Their Effect on Food Intake in Overweight and Obese Humans
OBJECTIVE: Peptide YY(3–36) (PYY(3–36)), a Y2 receptor agonist, and oxyntomodulin, a glucagon-like peptide 1 (GLP-1) receptor agonist, are cosecreted by intestinal L-cells after each meal. Separately each hormone acts as an endogenous satiety signal and reduces appetite in humans when infused intrav...
Autores principales: | Field, Benjamin C.T., Wren, Alison M., Peters, Veronique, Baynes, Kevin C.R., Martin, Niamh M., Patterson, Michael, Alsaraf, Sara, Amber, Vian, Wynne, Katie, Ghatei, Mohammad A., Bloom, Stephen R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889762/ https://www.ncbi.nlm.nih.gov/pubmed/20357366 http://dx.doi.org/10.2337/db09-1859 |
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