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γ-Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic β-Cells

OBJECTIVE: Paracrine signaling via γ-aminobutyric acid (GABA) and GABA(A) receptors (GABA(A)Rs) has been documented in rodent islets. Here we have studied the importance of GABAergic signaling in human pancreatic islets. RESEARCH DESIGN AND METHODS: Expression of GABA(A)Rs in islet cells was investi...

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Detalles Bibliográficos
Autores principales:	Braun, Matthias, Ramracheya, Reshma, Bengtsson, Martin, Clark, Anne, Walker, Jonathan N., Johnson, Paul R., Rorsman, Patrik
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889769/ https://www.ncbi.nlm.nih.gov/pubmed/20413510 http://dx.doi.org/10.2337/db09-0797

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