Cargando…

Redox Modulation Protects Islets From Transplant-Related Injury

OBJECTIVE: Because of reduced antioxidant defenses, β-cells are especially vulnerable to free radical and inflammatory damage. Commonly used antirejection drugs are excellent at inhibiting the adaptive immune response; however, most are harmful to islets and do not protect well from reactive oxygen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sklavos, Martha M., Bertera, Suzanne, Tse, Hubert M., Bottino, Rita, He, Jing, Beilke, Joshua N., Coulombe, Marilyne G., Gill, Ronald G., Crapo, James D., Trucco, Massimo, Piganelli, Jon D.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889773/ https://www.ncbi.nlm.nih.gov/pubmed/20413509 http://dx.doi.org/10.2337/db09-0588

Ejemplares similares

Pig-to-Nonhuman Primates Pancreatic Islet Xenotransplantation: An Overview
por: Marigliano, Marco, et al.
Publicado: (2011)

Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells “LAG-3-ing” Behind
por: Delmastro, Meghan M., et al.
Publicado: (2012)

The Future of Islet Transplantation Is Now
por: Bottino, Rita, et al.
Publicado: (2018)

Increased Yield and Improved Transplantation Outcome of Mouse Islets with Bovine Serum Albumin
por: Bertera, Suzanne, et al.
Publicado: (2012)

Hemoglobin A1C Percentage in Nonhuman Primates: A Useful Tool to Monitor Diabetes before and after Porcine Pancreatic Islet Xenotransplantation
por: Marigliano, Marco, et al.
Publicado: (2011)

Loss of NOX-Derived Superoxide Exacerbates Diabetogenic CD4 T-Cell Effector Responses in Type 1 Diabetes
por: Padgett, Lindsey E., et al.
Publicado: (2015)

Isolation of Human Islets for Autologous Islet Transplantation in Children and Adolescents with Chronic Pancreatitis
por: Bottino, Rita, et al.
Publicado: (2012)

Superoxide Production by Macrophages and T Cells Is Critical for the Induction of Autoreactivity and Type 1 Diabetes
por: Thayer, Terri C., et al.
Publicado: (2011)

Autologous Islet Transplantation After Total Pancreatectomy in a Patient Recovered from SARS-CoV-2: A Case Report
por: Tindall, Rachel P., et al.
Publicado: (2022)

Human Hemangioblast-Derived Mesenchymal Stem Cells Promote Islet Engraftment in a Minimal Islet Mass Transplantation Model in Mice
por: Bertera, Suzanne, et al.
Publicado: (2021)

Gene Combination Transfer to Block Autoimmune Damage in Transplanted Islets of Langerhans
por: Bertera, Suzanne, et al.
Publicado: (2004)

Donor Islet Endothelial Cells in Pancreatic Islet Revascularization
por: Nyqvist, Daniel, et al.
Publicado: (2011)

Viral Infection of Engrafted Human Islets Leads to Diabetes
por: Gallagher, Glen R., et al.
Publicado: (2015)

Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
por: Silva, Diego G., et al.
Publicado: (2011)

Markedly Decreased Blood Perfusion of Pancreatic Islets Transplanted Intraportally Into the Liver: Disruption of Islet Integrity Necessary for Islet Revascularization
por: Henriksnäs, Johanna, et al.
Publicado: (2012)

Increased Numbers of Low-Oxygenated Pancreatic Islets After Intraportal Islet Transplantation
por: Olsson, Richard, et al.
Publicado: (2011)

Autoimmunity in Autologous Islet Transplantation
por: Ali, Khawla F., et al.
Publicado: (2018)

Protection of Pancreatic Islets Using Theranostic Silencing Nanoparticles in a Baboon Model of Islet Transplantation
por: Pomposelli, Thomas, et al.
Publicado: (2020)

Redox-Dependent Inflammation in Islet Transplantation Rejection
por: Barra, Jessie M., et al.
Publicado: (2018)

Children With Islet Autoimmunity and Enterovirus Infection Demonstrate a Distinct Cytokine Profile
por: Yeung, Wing-Chi G., et al.
Publicado: (2012)

Optimizing Porcine Islet Isolation to Markedly Reduce Enzyme Consumption Without Sacrificing Islet Yield or Function
por: Holdcraft, Robert W., et al.
Publicado: (2016)

Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle: Establishment of a Vascular System Similar to That in Native Islets
por: Christoffersson, Gustaf, et al.
Publicado: (2010)

Cytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection
por: Schulte, Barbara M., et al.
Publicado: (2012)

Rituximab Selectively Suppresses Specific Islet Antibodies
por: Yu, Liping, et al.
Publicado: (2011)

Unexpected Acceleration of Type 1 Diabetes by Transgenic Expression of B7-H1 in NOD Mouse Peri-Islet Glia
por: Yantha, Jason, et al.
Publicado: (2010)

Slc11a1 Enhances the Autoimmune Diabetogenic T-Cell Response by Altering Processing and Presentation of Pancreatic Islet Antigens
por: Dai, Yang D., et al.
Publicado: (2009)

Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes
por: Arif, Sefina, et al.
Publicado: (2014)

Effectiveness of Intraoperative Versus Dedicated Islet Cell Laboratory Isolation for Total Pancreatectomy With Islet Autotransplant
por: Navas, Christopher M., et al.
Publicado: (2022)

Glucose and Inflammation Control Islet Vascular Density and β-Cell Function in NOD Mice: Control of Islet Vasculature and Vascular Endothelial Growth Factor by Glucose
por: Akirav, Eitan M., et al.
Publicado: (2011)

The Core Cysteines, (C909) of Islet Antigen-2 and (C945) of Islet Antigen-2β, Are Crucial to Autoantibody Binding in Type 1 Diabetes
por: Elvers, Karen T., et al.
Publicado: (2013)

Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice
por: Mangada, Julie, et al.
Publicado: (2009)

Endothelial Progenitor Cell Cotransplantation Enhances Islet Engraftment by Rapid Revascularization
por: Kang, Shinae, et al.
Publicado: (2012)

Mesenchymal Stem Cells Enhance Allogeneic Islet Engraftment in Nonhuman Primates
por: Berman, Dora M., et al.
Publicado: (2010)

Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation
por: Stocks, Blair T., et al.
Publicado: (2017)

Inhibition of Gelatinase B (Matrix Metalloprotease-9) Activity Reduces Cellular Inflammation and Restores Function of Transplanted Pancreatic Islets
por: Lingwal, Neelam, et al.
Publicado: (2012)

Islet Amyloid Polypeptide Is a Target Antigen for Diabetogenic CD4(+) T Cells
por: Delong, Thomas, et al.
Publicado: (2011)

Restoration of Glucose Counterregulation by Islet Transplantation in Long-standing Type 1 Diabetes
por: Rickels, Michael R., et al.
Publicado: (2015)

Assessment of β-Cell Mass and α- and β-Cell Survival and Function by Arginine Stimulation in Human Autologous Islet Recipients
por: Robertson, R. Paul, et al.
Publicado: (2015)

Bioenergetics of Islet Preparations in a Pilot Clinical Trial of Peri-Transplant Hydroxychloroquine for Autologous Islet Transplantation
por: McDowell, Ruth E., et al.
Publicado: (2021)

Oxidative Stress and Redox Modulation Potential in Type 1 Diabetes
por: Delmastro, Meghan M., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_45a9kn7m9ut73a29b64llev058