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Inhibition of Connective Tissue Growth Factor Overexpression in Diabetic Retinopathy by SERPINA3K via Blocking the WNT/β-Catenin Pathway

OBJECTIVE: Connective tissue growth factor (CTGF) is a major fibrogenic factor. Increased retinal CTGF levels have been implicated to play a role in diabetic retinopathy. SERPINA3K is a serine proteinase inhibitor, and its levels were decreased in retinas with diabetic retinopathy. The purpose of th...

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Detalles Bibliográficos
Autores principales:	Zhang, Bin, Zhou, Kevin K., Ma, Jian-xing
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889783/ https://www.ncbi.nlm.nih.gov/pubmed/20299474 http://dx.doi.org/10.2337/db09-1056

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