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Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats

OBJECTIVE: The hormone fibroblast growth factor 21 (FGF21) exerts diverse, beneficial effects on energy balance and insulin sensitivity when administered systemically to rodents with diet-induced obesity (DIO). The current studies investigate whether central FGF21 treatment recapitulates these effec...

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Detalles Bibliográficos
Autores principales:	Sarruf, David A., Thaler, Joshua P., Morton, Gregory J., German, Jonathan, Fischer, Jonathan D., Ogimoto, Kayoko, Schwartz, Michael W.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Pharmacology and Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889784/ https://www.ncbi.nlm.nih.gov/pubmed/20357365 http://dx.doi.org/10.2337/db09-1878

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