Cargando…

Resveratrol Inhibits Neuronal Apoptosis and Elevated Ca(2+)/Calmodulin-Dependent Protein Kinase II Activity in Diabetic Mouse Retina

OBJECTIVE: This study investigated the effects of resveratrol, a natural polyphenol with neuroprotective properties, on retinal neuronal cell death mediated by diabetes-induced activation of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII). RESEARCH DESIGN AND METHODS: Diabetes was induced in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Young-Hee, Kim, Yoon-Sook, Kang, Sang-Soo, Cho, Gyeong-Jae, Choi, Wan-Sung
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Pharmacology and Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889785/ https://www.ncbi.nlm.nih.gov/pubmed/20424226 http://dx.doi.org/10.2337/db09-1431

Ejemplares similares

Protein Kinase C-δ Mediates Neuronal Apoptosis in the Retinas of Diabetic Rats via the Akt Signaling Pathway
por: Kim, Young-Hee, et al.
Publicado: (2008)

Metabolic regulation of apoptosis via Ca+/Calmodulin Kinase II (CaMKII)
por: McCoy, Francis, et al.
Publicado: (2012)

Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart
por: Nassal, Drew, et al.
Publicado: (2020)

Ca(2+)/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy
por: Duran, Javier, et al.
Publicado: (2017)

Antiaging Gene Klotho Attenuates Pancreatic β-Cell Apoptosis in Type 1 Diabetes
por: Lin, Yi, et al.
Publicado: (2015)

Oestrogen inhibits resveratrol-induced post-translational modification of p53 and apoptosis in breast cancer cells
por: Zhang, S, et al.
Publicado: (2004)

Discovery of URAT1 SNPs and association between serum uric acid levels and URAT1
por: Cho, Sung Kweon, et al.
Publicado: (2015)

Insulin Reduces Cerebral Ischemia/Reperfusion Injury in the Hippocampus of Diabetic Rats: A Role for Glycogen Synthase Kinase-3β
por: Collino, Massimo, et al.
Publicado: (2009)

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro
por: Madlener, S, et al.
Publicado: (2010)

Lobe-specific Functions of Ca(2+)·Calmodulin in αCa(2+)·Calmodulin-dependent Protein Kinase II Activation
por: Jama, Abdirahman M., et al.
Publicado: (2011)

Biophysical analysis of the dynamics of calmodulin interactions with neurogranin and Ca(2+)/calmodulin‐dependent kinase II
por: Seeger, Christian, et al.
Publicado: (2017)

Inhibition of TRPP3 by calmodulin through Ca(2+)/calmodulin-dependent protein kinase II
por: Liu, Xiong, et al.
Publicado: (2023)

A Dynamic Model of Interactions of Ca(2+), Calmodulin, and Catalytic Subunits of Ca(2+)/Calmodulin-Dependent Protein Kinase II
por: Pepke, Shirley, et al.
Publicado: (2010)

Ca(2+)/Calmodulin and Apo-Calmodulin Both Bind to and Enhance the Tyrosine Kinase Activity of c-Src
por: Stateva, Silviya R., et al.
Publicado: (2015)

Ca(2+)/calmodulin-dependent Protein Kinases in Leukemia Development
por: Cui, Changhao, et al.
Publicado: (2021)

Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis
por: Loke, Yoon K, et al.
Publicado: (2015)

Prolyl Isomerase Pin1 Directly Regulates Calcium/Calmodulin-Dependent Protein Kinase II Activity in Mouse Brains
por: Shimizu, Taiki, et al.
Publicado: (2018)

Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis
por: Ulus-Senguloglu, G, et al.
Publicado: (2012)

Risk of gastrointestinal bleeding and cardiovascular events due to NSAIDs in the diabetic elderly population
por: Kim, Jungmee, et al.
Publicado: (2015)

Resveratrol Increases Nitric Oxide Production in the Rat Thick Ascending Limb via Ca(2+)/Calmodulin
por: Gonzalez-Vicente, Agustin, et al.
Publicado: (2014)

Calcium-/Calmodulin-Dependent Protein Kinase II (CaMKII) Inhibition Induces Learning and Memory Impairment and Apoptosis
por: Wang, Jialu, et al.
Publicado: (2021)

Investigation of Neuronal Cell Type-Specific Gene Expression of Ca(2+)/Calmodulin-dependent Protein Kinase II.
por: Mima, Kazuko, et al.
Publicado: (2002)

Fall incidents in nursing home residents: development of a predictive clinical rule (FINDER)
por: Milosevic, Vanja, et al.
Publicado: (2021)

Resveratrol Induces Glioma Cell Apoptosis through Activation of Tristetraprolin
por: Ryu, Jinhyun, et al.
Publicado: (2015)

Randomised, double-blind, parallel group, placebo-controlled study to evaluate the analgesic efficacy and safety of VVZ-149 injections for postoperative pain following laparoscopic colorectal surgery
por: Nedeljkovic, Srdjan S, et al.
Publicado: (2017)

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
por: Xu, Jing, et al.
Publicado: (2009)

Resveratrol Sensitizes Carfilzomib-Induced Apoptosis via Promoting Oxidative Stress in Multiple Myeloma Cells
por: Li, Qian, et al.
Publicado: (2018)

Molecular Mechanisms Underlying Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase Signal Transduction
por: Tokumitsu, Hiroshi, et al.
Publicado: (2022)

Src tyrosine kinase augments taxotere-induced apoptosis through enhanced expression and phosphorylation of Bcl-2
por: Boudny, V, et al.
Publicado: (2002)

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation
por: Rellos, Peter, et al.
Publicado: (2010)

Calmodulin-dependent protein phosphatase: immunocytochemical localization in chick retina
Publicado: (1985)

Mosloflavone-Resveratrol Hybrid TMS-HDMF-5z Exhibits Potent In Vitro and In Vivo Anti-Inflammatory Effects Through NF-κB, AP-1, and JAK/STAT Inactivation
por: Kim, Seo-Yeon, et al.
Publicado: (2022)

Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice
por: Gómez-Valadés, Alicia G., et al.
Publicado: (2008)

Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice
por: Tan, Carina P., et al.
Publicado: (2008)

Inhibition of Dipeptidyl Peptidase-4 by Vildagliptin During Glucagon-Like Peptide 1 Infusion Increases Liver Glucose Uptake in the Conscious Dog
por: Edgerton, Dale S., et al.
Publicado: (2009)

Activation of Peroxisome Proliferator–Activated Receptor-β/-δ (PPAR-β/-δ) Ameliorates Insulin Signaling and Reduces SOCS3 Levels by Inhibiting STAT3 in Interleukin-6–Stimulated Adipocytes
por: Serrano-Marco, Lucía, et al.
Publicado: (2011)

Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis
por: Conti, Roberto, et al.
Publicado: (2011)

Adiponectin Pretreatment Counteracts the Detrimental Effect of a Diabetic Environment on Endothelial Progenitors
por: Leicht, Simon F., et al.
Publicado: (2011)

Evaluation of the incremental cost to the National Health Service of prescribing analogue insulin
por: Holden, Sarah E, et al.
Publicado: (2011)

Non-steroidal anti-inflammatory drug (NSAID) related inhibition of aldosterone glucuronidation and arterial dysfunction in patients with rheumatoid arthritis: a cross-sectional clinical study
por: Crilly, Michael A, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_l1euodfqdmadvuej2dbm1uhjt8