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Vaccination with DNA Plasmids Expressing Gn Coupled to C3d or Alphavirus Replicons Expressing Gn Protects Mice against Rift Valley Fever Virus

BACKGROUND: Rift Valley fever (RVF) is an arthropod-borne viral zoonosis. Rift Valley fever virus (RVFV) is an important biological threat with the potential to spread to new susceptible areas. In addition, it is a potential biowarfare agent. METHODOLOGY/PRINCIPAL FINDINGS: We developed two potentia...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Nitin, Heise, Mark T., Ross, Ted M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889828/
https://www.ncbi.nlm.nih.gov/pubmed/20582312
http://dx.doi.org/10.1371/journal.pntd.0000725