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Transmembrane and Ubiquitin-Like Domain Containing 1 (Tmub1) Regulates Locomotor Activity and Wakefulness in Mice and Interacts with CAMLG

Tmub1 (C7orf21/HOPS) encodes a protein containing a ubiquitin-like domain. Tmub1 is highly expressed in the nervous system. To study its physiological function, we generated mice with Tmub1 deleted by homologous recombination. The knockout mice were grossly normal and viable. In a comprehensive beha...

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Detalles Bibliográficos
Autores principales: Zhang, Wandong, Savelieva, Katerina V., Suwanichkul, Adisak, Small, Daniel L., Kirkpatrick, Laura L., Xu, Nianhua, Lanthorn, Thomas H., Ye, Gui-Lan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889838/
https://www.ncbi.nlm.nih.gov/pubmed/20582322
http://dx.doi.org/10.1371/journal.pone.0011261