Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer

BACKGROUND: Estrogens suppress tumor growth in prostate cancer which progresses despite anorchid serum androgen levels, termed castration resistant prostate cancers (CRPC), although the mechanisms are unclear. We hypothesize that estrogen inhibits CRPC in anorchid animals by suppressing tumoral andr...

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Detalles Bibliográficos
Autores principales: Montgomery, Bruce, Nelson, Peter S, Vessella, Robert, Kalhorn, Tom, Hess, David, Corey , Eva
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889894/
https://www.ncbi.nlm.nih.gov/pubmed/20509933
http://dx.doi.org/10.1186/1471-2407-10-244

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