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Innate-Like Control of Human iNKT Cell Autoreactivity via the Hypervariable CDR3β Loop
Invariant Natural Killer T cells (iNKT) are a versatile lymphocyte subset with important roles in both host defense and immunological tolerance. They express a highly conserved TCR which mediates recognition of the non-polymorphic, lipid-binding molecule CD1d. The structure of human iNKT TCRs is uni...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889927/ https://www.ncbi.nlm.nih.gov/pubmed/20585371 http://dx.doi.org/10.1371/journal.pbio.1000402 |