Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-κB signaling-induced gene expression responses in inflammation

BACKGROUND: Signal transduction is the major mechanism through which cells transmit external stimuli to evoke intracellular biochemical responses. Diverse cellular stimuli create a wide variety of transcription factor activities through signal transduction pathways, resulting in different gene expre...

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Detalles Bibliográficos
Autores principales: Peng, Shih Chi, Wong, David Shan Hill, Tung, Kai Che, Chen, Yan Yu, Chao, Chun Cheih, Peng, Chien Hua, Chuang, Yung Jen, Tang, Chuan Yi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889938/
https://www.ncbi.nlm.nih.gov/pubmed/20529327
http://dx.doi.org/10.1186/1471-2105-11-308

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