Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigs

BACKGROUND: CJ9-gD is a novel dominant-negative recombinant herpes simplex virus type 1 (HSV-1) that is completely replication-defective, cannot establish detectable latent infection in vivo, and expresses high levels of the major HSV-1 antigen glycoprotein D immediately following infection. In the...

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Detalles Bibliográficos
Autores principales: Brans, Richard, Yao, Feng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889954/
https://www.ncbi.nlm.nih.gov/pubmed/20525279
http://dx.doi.org/10.1186/1471-2180-10-163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889954/
https://www.ncbi.nlm.nih.gov/pubmed/20525279
http://dx.doi.org/10.1186/1471-2180-10-163

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