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Comparison of Entropic Contributions to Binding in a “Hydrophilic” versus “Hydrophobic” Ligand−Protein Interaction

[Image: see text] In the present study we characterize the thermodynamics of binding of histamine to recombinant histamine-binding protein (rRaHBP2), a member of the lipocalin family isolated from the brown-ear tick Rhipicephalus appendiculatus. The binding pocket of this protein contains a number o...

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Detalles Bibliográficos
Autores principales: Syme, Neil R., Dennis, Caitriona, Bronowska, Agnieszka, Paesen, Guido C., Homans, Steve W.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890244/
https://www.ncbi.nlm.nih.gov/pubmed/20524663
http://dx.doi.org/10.1021/ja101362u