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An information-flow-based model with dissipation, saturation and direction for active pathway inference

BACKGROUND: Biological systems process the genetic information and environmental signals through pathways. How to map the pathways systematically and efficiently from high-throughput genomic and proteomic data is a challenging open problem. Previous methods design different heuristics but do not des...

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Detalles Bibliográficos
Autores principales: Ren, Xianwen, Zhou, Xiaobo, Wu, Ling-Yun, Zhang, Xiang-Sun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890502/
https://www.ncbi.nlm.nih.gov/pubmed/20504374
http://dx.doi.org/10.1186/1752-0509-4-72