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Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases
BACKGROUND: Kynurenine aminotransferase (KAT) catalyzes the transamination of kynunrenine to kynurenic acid (KYNA). KYNA is a neuroactive compound and functions as an antagonist of alpha7-nicotinic acetylcholine receptors and is the only known endogenous antagonist of N-methyl-D-aspartate receptors....
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890522/ https://www.ncbi.nlm.nih.gov/pubmed/20482848 http://dx.doi.org/10.1186/1471-2091-11-19 |