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Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung cancer in vitro and in vivo

BACKGROUND: Non-small cell lung cancer (NSCLC) is the leading cause of cancer related mortality, any improvements in therapeutic strategies are urgently required. In this study we generated a novel 'suicide gene' armed oncolytic adenoviral vector and investigated its antitumor effect both...

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Detalles Bibliográficos
Autores principales:	Zhang, Ju-Feng, Wei, Fang, Wang, Hui-Ping, Li, Hui-Ming, Qiu, Wei, Ren, Peng-Kang, Chen, Xia-Fang, Huang, Qian
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890545/ https://www.ncbi.nlm.nih.gov/pubmed/20487549 http://dx.doi.org/10.1186/1756-9966-29-52

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