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Efficient inhibition of lung cancer in murine model by plasmid-encoding VEGF short hairpin RNA in combination with low-dose DDP

BACKGROUND: VEGF is a well-validated target for antiangiogenic intervention in cancer. To date, RNAi technology has been proven to be a promising approach for targeted therapy. DDP is frequently used as a first-line drug in chemotherapy for lung cancer but usually causes severe toxicity. In this stu...

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Detalles Bibliográficos
Autores principales:	Ma, Yong P, Yang, Yang, Zhang, Shuang, Chen, Xiang, Zhang, Na, Wang, Wei, Cao, Zhi X, Jiang, Yu, Zhao, Xia, Wei, Yu Q, Deng, Hong X
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890548/ https://www.ncbi.nlm.nih.gov/pubmed/20497582 http://dx.doi.org/10.1186/1756-9966-29-56

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