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Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs

PURPOSE: Constitutively decreased TGFBR1 allelic expression is emerging as a potent modifier of colorectal cancer risk in mice and humans. This phenotype was first observed in mice, then in lymphoblastoid cell lines from patients with microsatellite stable colorectal tumors. PATIENTS AND METHODS: We...

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Detalles Bibliográficos
Autores principales:	Pasche, Boris, Wisinski, Kari B, Sadim, Maureen, Kaklamani, Virginia, Pennison, Michael J, Zeng, Qinghua, Bellam, Naresh, Zimmerman, Jacquelyn, Yi, Nengjun, Zhang, Kui, Baron, John, Stram, Daniel O, Hayes, M Geoffrey
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890549/ https://www.ncbi.nlm.nih.gov/pubmed/20500843 http://dx.doi.org/10.1186/1756-9966-29-57

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