Targeting the Transforming Growth Factor-β pathway inhibits human basal-like breast cancer metastasis

BACKGROUND: Transforming Growth Factor β (TGF-β) plays an important role in tumor invasion and metastasis. We set out to investigate the possible clinical utility of TGF-β antagonists in a human metastatic basal-like breast cancer model. We examined the effects of two types of the TGF-β pathway anta...

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Detalles Bibliográficos
Autores principales: Ganapathy, Vidya, Ge, Rongrong, Grazioli, Alison, Xie, Wen, Banach-Petrosky, Whitney, Kang, Yibin, Lonning, Scott, McPherson, John, Yingling, Jonathan M, Biswas, Swati, Mundy, Gregory R, Reiss, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890606/
https://www.ncbi.nlm.nih.gov/pubmed/20504320
http://dx.doi.org/10.1186/1476-4598-9-122

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