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HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling

BACKGROUND: Androgen signaling plays a critical role in the development of prostate cancer and its progression. However, androgen-independent prostate cancer cells emerge after hormone ablation therapy, resulting in significant clinical problems. We have previously demonstrated that the HOXB13 homeo...

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Detalles Bibliográficos
Autores principales: Kim, Young-Rang, Oh, Kyung-Jin, Park, Ra-Young, Xuan, Nguyen Thi, Kang, Taek-Won, Kwon, Dong-Deuk, Choi, Chan, Kim, Min Soo, Nam, Kwang Il, Ahn, Kyu Youn, Jung, Chaeyong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890607/
https://www.ncbi.nlm.nih.gov/pubmed/20504375
http://dx.doi.org/10.1186/1476-4598-9-124