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Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives

BACKGROUND: A maximum entropy approach is proposed to predict the cytotoxic effects of a panel of colchicine derivatives in several human cancer cell lines. Data was obtained from cytotoxicity assays performed with 21 drug molecules from the same family of colchicine compounds and correlate these re...

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Detalles Bibliográficos
Autores principales:	Tseng, Chih-Yuan, Mane, Jonathan Y, Winter, Philip, Johnson, Lorelei, Huzil, Torin, Izbicka, Elzbieta, Luduena, Richard F, Tuszynski, Jack A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890610/ https://www.ncbi.nlm.nih.gov/pubmed/20509970 http://dx.doi.org/10.1186/1476-4598-9-131

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