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ApoE mimetic peptide decreases Aβ production in vitro and in vivo

BACKGROUND: Apolipoprotein E (apoE) is postulated to affect brain Aβ levels through multiple mechanisms--by altering amyloid precursor protein (APP) processing, Aβ degradation, and Aβ clearance. We previously showed that an apoE-derived peptide containing a double repeat of the receptor-binding regi...

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Detalles Bibliográficos
Autores principales:	Minami, S Sakura, Cordova, Antoinette, Cirrito, John R, Tesoriero, Joseph A, Babus, Lenard W, Davis, Gary C, Dakshanamurthy, Sivanesan, Turner, R Scott, Pak, Daniel TS, Rebeck, G William, Paige, Mikell, Hoe, Hyang-Sook
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890633/ https://www.ncbi.nlm.nih.gov/pubmed/20406479 http://dx.doi.org/10.1186/1750-1326-5-16

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