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A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease
BACKGROUND: The inability of aspirin (ASA) to adequately suppress platelet aggregation is associated with future risk of coronary artery disease (CAD). Heritability studies of agonist-induced platelet function phenotypes suggest that genetic variation may be responsible for ASA responsiveness. In th...
Autores principales: | Mathias, Rasika A, Kim, Yoonhee, Sung, Heejong, Yanek, Lisa R, Mantese, VJ, Hererra-Galeano, J Enrique, Ruczinski, Ingo, Wilson, Alexander F, Faraday, Nauder, Becker, Lewis C, Becker, Diane M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890666/ https://www.ncbi.nlm.nih.gov/pubmed/20529293 http://dx.doi.org/10.1186/1755-8794-3-22 |
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