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Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

BACKGROUND: Experimental evidence suggests that xanthine oxidase inhibitors can reduce myocardial oxygen consumption for a particular stroke volume. If such an effect also occurs in man, this class of inhibitors could become a new treatment for ischaemia in patients with angina pectoris. We ascertai...

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Detalles Bibliográficos
Autores principales: Noman, Awsan, Ang, Donald SC, Ogston, Simon, Lang, Chim C, Struthers, Allan D
Formato: Texto
Lenguaje:English
Publicado: Lancet Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890860/
https://www.ncbi.nlm.nih.gov/pubmed/20542554
http://dx.doi.org/10.1016/S0140-6736(10)60391-1