Cargando…

Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs

Understanding individual differences in the susceptibility to metabolic side effects as a response to antipsychotic therapy is essential to optimize the treatment of schizophrenia. Here we perform genomewide association studies (GWAS) to search for genetic variation affecting the susceptibility to m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adkins, Daniel E., Åberg, Karolina, McClay, Joseph L., Bukszár, József, Zhao, Zhongming, Jia, Peilin, Stroup, T. Scott, Perkins, Diana, McEvoy, Joseph P., Lieberman, Jeffrey A., Sullivan, Patrick F., van den Oord, Edwin J.C.G.
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891163/ https://www.ncbi.nlm.nih.gov/pubmed/20195266 http://dx.doi.org/10.1038/mp.2010.14

Ejemplares similares

Genomewide Pharmacogenomic Analysis of Response to Treatment with Antipsychotics
por: McClay, Joseph L., et al.
Publicado: (2009)

Genome-wide association study of antipsychotic induced QTc interval prolongation
por: Åberg, Karolina, et al.
Publicado: (2010)

Estimation of CpG coverage in whole methylome next-generation sequencing studies
por: van den Oord, Edwin JCG, et al.
Publicado: (2013)

Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR(*)D
por: Adkins, D E, et al.
Publicado: (2012)

Comparative effectiveness of antipsychotic drugs in schizophrenia
por: Stroup, T. Scott, et al.
Publicado: (2000)

Estimating the number and size of the main effects in genome-wide case-control association studies
por: Kuo, Po-Hsiu, et al.
Publicado: (2007)

Genomewide Association Studies in Pharmacogenomics
por: McInnes, Gregory, et al.
Publicado: (2021)

Genotype-Based Ancestral Background Consistently Predicts Efficacy and Side Effects across Treatments in CATIE and STAR*D
por: Adkins, Daniel E., et al.
Publicado: (2013)

A method to improve the reproducibility of findings from epigenome- and transcriptome-wide association studies
por: van den Oord, Edwin JCG, et al.
Publicado: (2023)

Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity
por: McEvoy, L., et al.
Publicado: (2021)

Enrichment methods provide a feasible approach to comprehensive and adequately powered investigations of the brain methylome
por: Chan, Robin F., et al.
Publicado: (2017)

High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction
por: McClay, Joseph L., et al.
Publicado: (2015)

High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot
por: Aberg, Karolina A., et al.
Publicado: (2013)

Genome-Wide and Gene-Based Association Studies of Anxiety Disorders in European and African American Samples
por: Otowa, Takeshi, et al.
Publicado: (2014)

Controversies Surrounding the Use of Long-Acting Injectable Antipsychotic Medications for the Treatment of Patients with Schizophrenia
por: Kane, John M., et al.
Publicado: (2021)

In Silico Whole Genome Association Scan for Murine Prepulse Inhibition
por: Webb, Bradley Todd, et al.
Publicado: (2009)

Pharmacogenomics: A focus on antidepressants and atypical antipsychotics
por: Lister, Jonathan F.
Publicado: (2016)

MethylPCA: a toolkit to control for confounders in methylome-wide association studies
por: Chen, Wenan, et al.
Publicado: (2013)

Epigenetic regulation of drug metabolism in aging
por: McClay, Joseph L.
Publicado: (2021)

Association of genomewide newborn DNA methylation patterns with maternal and newborn characteristics
por: Adkins, Ronald M, et al.
Publicado: (2010)

Differing response to antipsychotic therapy in schizophrenia: pharmacogenomic aspects
por: Ackenheil, Manfred, et al.
Publicado: (2004)

Treatment-resistant schizophrenia: current insights on the pharmacogenomics of antipsychotics
por: Lally, John, et al.
Publicado: (2016)

Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium
por: Verma, Shefali Setia, et al.
Publicado: (2020)

Pharmacogenomics and clinical response to antipsychotic treatment. Expectations vs reality.
por: Papadimitriou, N., et al.
Publicado: (2023)

Fine-grained cell-type specific association studies with human bulk brain data using a large single-nucleus RNA sequencing based reference panel
por: van den Oord, Edwin J. C. G., et al.
Publicado: (2023)

Overestimation of the classification accuracy of a biomarker for assessing heavy alcohol use
por: Hattab, Mohammad W, et al.
Publicado: (2018)

Perityphlitis
por: McEvoy, Joseph
Publicado: (1891)

Effectiveness of lurasidone in schizophrenia or schizoaffective patients switched from other antipsychotics: a 6-month, open-label, extension study
por: Citrome, Leslie, et al.
Publicado: (2013)

Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics
por: McEvoy, Joseph, et al.
Publicado: (2013)

Antipsychotic pharmacogenomics in first episode psychosis: a role for glutamate genes
por: Stevenson, J M, et al.
Publicado: (2016)

Teoría cuántica para principiantes
por: McEvoy, Joseph P.
Publicado: (1998)

Genomewide characterization of non-polyadenylated RNAs
por: Yang, Li, et al.
Publicado: (2011)

Genomewide Association Study of Simvastatin Pharmacokinetics
por: Mykkänen, Anssi J. H., et al.
Publicado: (2022)

ANTIPSYCHOTIC-INDUCED VACUOUS CHEWING MOVEMENTS AND EXTRAPYRAMIDAL SIDE-EFFECTS ARE HIGHLY HERITABLE IN MICE
por: Crowley, James J., et al.
Publicado: (2010)

Protocol for a pharmacogenomic study on individualised antipsychotic drug treatment for patients with schizophrenia
por: Su, Yi, et al.
Publicado: (2021)

MEAN cookbook: the meanest set of MEAN stack solutions around MongoDB, Express, AngularJS, and Node.js
por: McClay, Nicholas
Publicado: (2017)

A Magnetoencephalographic/Encephalographic (MEG/EEG) Brain-Computer Interface Driver for Interactive iOS Mobile Videogame Applications Utilizing the Hadoop Ecosystem, MongoDB, and Cassandra NoSQL Databases
por: McClay, Wilbert
Publicado: (2018)

Implementation of the Family HELP Protocol: A Feasibility Project for a West Texas ICU
por: McClay, Rebecca
Publicado: (2021)

Estimation of significance thresholds for genomewide association scans
por: Dudbridge, Frank, et al.
Publicado: (2008)

A Genomewide Functional Network for the Laboratory Mouse
por: Guan, Yuanfang, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_vvdoh6qqp5qr6mji28862g8ae8