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Protein Folding Requires Crowd Control in a Simulated Cell
Macromolecular crowding has a profound effect upon biochemical processes in the cell. We have computationally studied the effect of crowding upon protein folding for 12 small domains in a simulated cell using a coarse-grained protein model, which is based upon Langevin dynamics, designed to unify th...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891488/ https://www.ncbi.nlm.nih.gov/pubmed/20149797 http://dx.doi.org/10.1016/j.jmb.2010.01.074 |