Cargando…
Protein Folding Requires Crowd Control in a Simulated Cell
Macromolecular crowding has a profound effect upon biochemical processes in the cell. We have computationally studied the effect of crowding upon protein folding for 12 small domains in a simulated cell using a coarse-grained protein model, which is based upon Langevin dynamics, designed to unify th...
Autores principales: | Jefferys, Benjamin R., Kelley, Lawrence A., Sternberg, Michael J.E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891488/ https://www.ncbi.nlm.nih.gov/pubmed/20149797 http://dx.doi.org/10.1016/j.jmb.2010.01.074 |
Ejemplares similares
-
Folding in a crowd
por: LeBrasseur, Nicole
Publicado: (2005) -
RNA Hairpin Folding in the Crowded Cell
por: Gao, Mimi, et al.
Publicado: (2016) -
Crowded environments tune the fold-switching in metamorphic proteins
por: Zhang, Ning, et al.
Publicado: (2023) -
The AlphaFold Database of Protein Structures: A Biologist’s Guide
por: David, Alessia, et al.
Publicado: (2022) -
Simulations of a protein fold switch reveal crowding-induced population shifts driven by disordered regions
por: Bazmi, Saman, et al.
Publicado: (2023)