Reduced evolvability of Escherichia coli MDS42, an IS-less cellular chassis for molecular and synthetic biology applications

BACKGROUND: Evolvability is an intrinsic feature of all living cells. However, newly emerging, evolved features can be undesirable when genetic circuits, designed and fabricated by rational, synthetic biological approaches, are installed in the cell. Streamlined-genome E. coli MDS42 is free of mutat...

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Detalles Bibliográficos
Autores principales: Umenhoffer, Kinga, Fehér, Tamás, Balikó, Gabriella, Ayaydin, Ferhan, Pósfai, János, Blattner, Frederick R, Pósfai, György
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891674/
https://www.ncbi.nlm.nih.gov/pubmed/20492662
http://dx.doi.org/10.1186/1475-2859-9-38

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