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Brca2 and Trp53 Deficiency Cooperate in the Progression of Mouse Prostate Tumourigenesis
Epidemiological studies have shown that one of the strongest risk factors for prostate cancer is a family history of the disease, suggesting that inherited factors play a major role in prostate cancer susceptibility. Germline mutations in BRCA2 predispose to breast and ovarian cancer with its predom...
Autores principales: | Francis, Jeffrey C., McCarthy, Afshan, Thomsen, Martin K., Ashworth, Alan, Swain, Amanda |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891704/ https://www.ncbi.nlm.nih.gov/pubmed/20585617 http://dx.doi.org/10.1371/journal.pgen.1000995 |
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