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Brca2 and Trp53 Deficiency Cooperate in the Progression of Mouse Prostate Tumourigenesis

Epidemiological studies have shown that one of the strongest risk factors for prostate cancer is a family history of the disease, suggesting that inherited factors play a major role in prostate cancer susceptibility. Germline mutations in BRCA2 predispose to breast and ovarian cancer with its predom...

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Detalles Bibliográficos
Autores principales: Francis, Jeffrey C., McCarthy, Afshan, Thomsen, Martin K., Ashworth, Alan, Swain, Amanda
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891704/
https://www.ncbi.nlm.nih.gov/pubmed/20585617
http://dx.doi.org/10.1371/journal.pgen.1000995

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