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Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization
Defensins are effectors of the innate immune response with potent antibacterial activity. Their role in antiviral immunity, particularly for non-enveloped viruses, is poorly understood. We recently found that human alpha-defensins inhibit human adenovirus (HAdV) by preventing virus uncoating and rel...
Autores principales: | Smith, Jason G., Silvestry, Mariena, Lindert, Steffen, Lu, Wuyuan, Nemerow, Glen R., Stewart, Phoebe L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891831/ https://www.ncbi.nlm.nih.gov/pubmed/20585634 http://dx.doi.org/10.1371/journal.ppat.1000959 |
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