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The Enteropathogenic E. coli Effector EspF Targets and Disrupts the Nucleolus by a Process Regulated by Mitochondrial Dysfunction
The nucleolus is a multifunctional structure within the nucleus of eukaryotic cells and is the primary site of ribosome biogenesis. Almost all viruses target and disrupt the nucleolus—a feature exclusive to this pathogen group. Here, using a combination of bio-imaging, genetic and biochemical analys...
Autores principales: | Dean, Paul, Scott, Jon A., Knox, Andrew A., Quitard, Sabine, Watkins, Nicholas J., Kenny, Brendan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891835/ https://www.ncbi.nlm.nih.gov/pubmed/20585567 http://dx.doi.org/10.1371/journal.ppat.1000961 |
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