The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment

Sensitization to inflammatory pain is a pathological form of neuronal plasticity that is poorly understood and treated. Here we examine the role of the SH3 domain of postsynaptic density 95 (PSD95) by using mice that carry a single amino-acid substitution in the polyproline-binding site. Testing mul...

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Detalles Bibliográficos
Autores principales: Arbuckle, Margaret I, Komiyama, Noboru H, Delaney, Ada, Coba, Marcelo, Garry, Emer M, Rosie, Roberta, Allchorne, Andrew J, Forsyth, Lynsey H, Bence, Matthew, Carlisle, Holly J, O'Dell, Thomas J, Mitchell, Rory, Fleetwood-Walker, Susan M, Grant, Seth G N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892321/
https://www.ncbi.nlm.nih.gov/pubmed/20467438
http://dx.doi.org/10.1038/embor.2010.63

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